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February 13, 2006

Funding of new grant award of $2 million for 4 years by  USAMRAA PRMRP (PR054755: "Novel Nitroxide Resuscitation Strategies in Experimental Traumatic Brain Injury", a collaborative project between Safar Center for Resuscitation Research and SynZyme Technologies LLC)

 

January 27, 2006

Publication of a manuscript by scientists in the Department of Medicine at Albert Einstein College of Medicine and at SynZyme entitled Inhibition of Sickle Red Cell Adhesion and Vaso-occlusion in the Microcirculation by Antioxidants” in the Am J Physiol Heart Circ Physiol showing PNAs potential to ameliorate sickle (SS) red cell adhesion and the related vaso-occlusion in sickle cell disease.

 

January 20, 2006

Meeting with the FDA regarding VACNO® for Exploratory IND

 

October 6 2005

Opened a production facility for SynZyme drug intermediates in TainJin, China

 

September 12 2005 

Selected to participate in NIH-CAP program

 

July 27, 2005 

Funding of new grant award to SynZyme Technologies LLC of $3 million for 3 years by NINDS (2R44NS036119-04: “PNA for Stroke”)

 

 April 27 2005

Publication of a manuscript entitled “Polynitroxyl albumin inhibits inflammation and vasoocclusion in transgenic sickle mice” in the J Lab Clin Med. (vol 145(4): pg 204-11) showing PNA’s possible efficacy to prevent painful vaso-occlusion in sickle cell disease.

 

February 2, 2005 

Pre-IND Meeting with the FDA regarding HemoZyme® development

 

November 23, 2004 

Granted extension of US the Army grant for Polynitroxyl Albumin plus Tempol (PNA + Tempol) for Combat Casualty Care: Phase I Human Trial

 

October 27, 2004

Pre-IND meeting with FDA regarding VACNO® for stroke

 

May 6, 2004 

Pre-IND meeting with FDA regarding VACNO® for Sickle Cell Disease

 


 

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