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Selected Peer-Reviewed Publications

1.         DK Kaul, XD Liu, X Zhang, L Ma, CJ Hsia, RL Nagel. “Inhibition of Sickle Red Cell Adhesion and Vaso-occlusion in the Microcirculation by Antioxidants”. Am J Physiol Heart Circ Physiol. Jan 27 (2006)

2.         H Mahaseth, GM Vercellotti, TE Welch, PR Bowlin, KM Sonbol, C.J Hsia, L Ma, JC Bischof, RP Hebbel, and JD Belcher. “Polynitroxyl albumin inhibits inflammation and vasoocclusion in transgenic sickle mice”. J Lab Clin Med. 145(4):204-11 (2005)

3.         PW Buehler, CR Haney, A Gulati, L Ma, C.J Hsia. “Polynitroxyl hemoglobin: a pharmacokinetic study of covalently bound nitroxides to hemoglobin platforms” Free Radic Biol Med. 37(1):124-35 (2004)

4.         A Weinberg, KD Nylander, C Yan, L Ma, C.J Hsia, VA Tyurin, VE Kagan, NF Schor. “Prevention of catecholaminergic oxidative toxicity by 4-hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl and its recycling complex with polynitroxylated albumin, TEMPOL/PNA”, Brain Res. 1012(1-2):13-21 (2004)

5.         R Kentner, P Safar, W Behringer, X Wu, VE Kagan, YY Tyurina, J Henchir, L Ma, C.J Hsia, SA Tisherman. “Early antioxidant therapy with Tempol during hemorrhagic shock increases survival in rats.” J Trauma. 53(5):968-77 (2002)

6.         H. Li, L. Ma, C.J. Hsia, J.L. Zweier and P. Kuppusamy, “Polynitroxyl-Albumin (PNA) Enhances Myocardial Infarction Therapeutic Effect of TEMPOL in Rat Hearts Subjected to Regional Ischemia-Reperfusion,” Free Radical Biology and Medicine 32, 712-9 (2002)

7.         J.H. Park, L. Ma, T. Oshima, P. Carter, L. Coe, J.W. Ma, R. Specian, M.B. Grisham, C.E. Trimble, C.J. Hsia, J.E. Liu and J.S. Alexander, “Polynitroxylated Starch/TPL Attenuates Cachexia and Increased Epithelial Permeability Associated with TNBS Colitis,” Inflammation 26, 1-11 (2002)

8.         T. Sugawara, F. Yu, Li Ma, C.J.C. Hsia and P.H. Chan, “Delayed Treatment With Polynitroxyl Albumin Reduces Infarct Size After Stroke in Rats,” NeuroReport 12, 3609-12 (2001)

9.         J.M. Blonder, T.A. McCalden, C.J.C. Hsia and R.E. Billings, “Polynitroxyl Albumin Plus Tempol Attenuates Liver Injury and Inflammation After Hepatic Ischemia and Reperfusion,” Life Sciences 67, 3231-9 (2000)

10.     PW Buehler, S Mehendale, H Wang, J Xie, L Ma, CE Trimble, C.J Hsia, A Gulati. “Resuscitative effects of polynitroxylated alphaalpha-cross-linked hemoglobin following severe hemorrhage in the rat” Free Radic Biol Med. Oct 15;29(8):764-74 (2000)

11.     S. Zhang, H. Li, Li Ma, C. Trimble, P. Kuppusamy, D.L. Carden and C.J.C. Hsia, “Polynitroxyl Albumin (PNA) Plus Tempol Attenuate Lung Capillary Leak Elicited by Prolonged Intestinal Ischemia and Reperfusion,” Free Radical Biology and Medicine 29, 42-50 (2000).

12.     M Steinbauer, M Guba, M Buchner, S Farkas, M Anthuber, and KW Jauch, “Impact of polynitroxylated albumin (PNA) and tempol on ischemia/reperfusion injury: intravital microscopic study in the dorsal skinfold chamber of the Syrian golden hamster”. Shock  14,163-168 (2000)

13.     RA Maxwell, JB Gibson, TC Fabian, and KG Proctor,“Resuscitation of severe chest trauma with four different hemoglobin-based oxygen-carrying solutions”, J Trauma. 49(2):200-11 (2000)

14.     R.K. Saetzler, K.E. Arfors, R.F. Tuma, U. Vasthare, Li Ma, C.J.C. Hsia and H. Lehr, "Polynitroxylated Hemoglobin-Based Oxygen Carrier: Inhibition of Free Radical-Induced Microcirculatory Dysfunction," Free Radical Biology & Medicine 27, 1-6 (1999)

15.     N. Okayama, J. Park, L. Coe, D.N. Granger, Li Ma, C.J.C. Hsia and J.S. Alexander, "Polynitroxyl αα-Hemoglobin (PNH) Inhibits Peroxide and Superoxide-Mediated Neutrophil Adherence to Human Endothelial Cells," Free Radical Research 31, 53-58 (1999)

16.     P. Kuppusamy, P. Wang, R.A. Shankar, Li Ma, C. Trimble, C.J.C. Hsia and J.L. Zweier, "In Vivo Topical EPR Spectroscopy and Imaging of Nitroxide Free Radicals and Polynitroxyl-Albumin," Magnetic Resonance in Medicine 40, 806-11 (1998)

17.     C. Beaulieu, E. Busch, J. Rother, A.D. Crespigny, C.J.C. Hsia and M.E. Moseley, "Polynitroxyl Albumin Reduces Infarct Size In Transient Focal Cerebral Ischemia In The Rat: Potential Mechanisms Studied By Magnetic Resonance Imaging," Journal of Cerebral Blood Flow and Metabolism 18, 1022-31 (1998)

18.     J. Russell, N. Okayama, J.S. Alexander, D.N. Granger and C.J. Hsia, "Pretreatment With Polynitroxyl Albumin (PNA) Inhibits Ischemia-Reperfusion Induced Leukocyte-Endothelial Cell Adhesion," Free Radical Biology & Medicine 25, 153-9 (1998)

19.     Kuppusamy, P. Wang, J. Zweier, M. Krishna, J. Mitchell, L Ma, C. Trimble, and C.J. Hsia, "Electron Paramagnetic Resonance Imaging of Rat Heart with Nitroxide and Polynitroxide-albumin", P. Biochemistry, 35: 7051-7 (1996)


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